Publications

The Myelin Repair Foundation (MRF) is committed to advancing research as rapidly as possible through prompt publication of results.

Here is a list of recent publications resulting from MRF funding:

Ben Barres

1. Dugas, Jason C.; Tai, Yu Chuan; Speed, Terence P.; Ngai, John; Barres, Ben A..   Functional genomic analysis of oligodendrocyte differentiation.    Journal of Neuroscience  (2006),  26(43),  10967-10983.
2. Watkins, T. A., Emery, B., Mulinyawe, S. & Barres, B. A. (2007)  A critical period for myelination by oligodendrocytes. (in preparation).
3. Dugas J.C., Ibrahim A., and Barres B.A. (2007). A Crucial Role for p57Kip2 in the Intracellular Timer that Controls Oligodendrocyte Differentiation. J. Neuroscience, in review.
4. Cahoy J, Emery B, Barres B (2007) Gene profiling analysis of astrocytes, oligodendrocytes, and neurons (in preparation).
5. Gould R.M., Goldstone J.V., and Dugas J.C. (2007). The evolution of myelination: interactions of recently-evolved proteins with pre-existing lipid moieties may have produced the first vertebrate compact myelin. Nature, in review.
6. Daneman R., Barres BA (2007) Pericytes regulate the blood-brain barrier during embryogenesis (In preparation)
7. Daneman R., Agalliu D., Zhou L., Barres BA (2007) Genomic Analysis of the Blood-brain Barrier.  (In preparation)
8. Daneman R.,  Rumah KR., and Barres BA (2007) Activation of EBA, a variant of Ngr2, leads to transient breakdown of the BBB (In preparation)
9. Daneman R.  Rumah KR.  Zhou L. Barres BA (2007) Hemoglobin: A novel component of the blood-brain barrier (In preparation)

Stephen D. Miller

1. Schreiner, Bettina; Bailey, Samantha L.; Miller, Stephen D..   T-cell response dynamics in animal models of multiple sclerosis: implications for immunotherapies.    Expert Review of Clinical Immunology  (2007),  3(1),  57-72.
2. Bailey, Samantha L.; Schreiner, Bettina; McMahon, Eileen J.; Miller, Stephen D..   CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ TH-17 cells in relapsing EAE.    Nature Immunology  (2006),  Volume Date 2007,  8(2),  172-180.
3. Bailey, Samantha L.; Carpentier, Pamela A.; McMahon, Eileen J.; Begolka, Wendy Smith; Miller, Stephen D..   Innate and adaptive immune responses of the central nervous system.    Critical Reviews in Immunology  (2006),  26(2),  149-188. 

Robert H. Miller

1. Bai, Lianhua; Caplan, Arnold; Lennon, Donald; Miller, Robert H..   Human Mesenchymal Stem Cells Signals Regulate Neural Stem Cell Fate.    Neurochemical Research  (2007),  32(2),  353-362.
2. Gao, Limin; Miller, Robert H..   Specification of optic nerve oligodendrocyte precursors by retinal ganglion cell axons.    Journal of Neuroscience  (2006),  26(29),  7619-7628.
3. Miller, Robert H..   The promise of stem cells for neural repair.    Brain Research  (2006),  1091(1),  258-264.
4. Gao, Limin; Miller, Robert H..   Cytokines and development of the nervous system.    Cytokines and the CNS (2nd Edition)  (2006),     93-112.
5. Tsai, Hui-Hsin; Macklin, Wendy B.; Miller, Robert H..   Netrin-1 is required for the normal development of spinal cord oligodendrocytes.    Journal of Neuroscience  (2006),  26(7),  1913-1922.
6. Gao, Limin; Macklin, Wendy; Gerson, James; Miller, Robert H..   Intrinsic and extrinsic inhibition of oligodendrocyte development by rat retina.    Developmental Biology (San Diego, CA, United States)  (2006),  290(2),  277-286.
7. Padovani-Claudio Dolly A; Liu Liping; Ransohoff Richard M; Miller Robert H   Alterations in the oligodendrocyte lineage, myelin, and white matter in adult mice lacking the chemokine receptor CXCR2.    Glia  (2006),  54(5),  471-83.

Brian Popko

1. Lin, Wensheng; Bailey, Samantha L.; Ho, Hanson; Harding, Heather P.; Ron, David; Miller, Stephen D.; Popko, Brian.   The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage.    Journal of Clinical Investigation  (2007),  117(2),  448-456.
2. Popko, Brian; Lin, Wensheng.   An animal expressing INF-gamma  transgene and having altered expression of endoplasmic reticulum stress-correlated gene as demyelination disorder model, and drug screening uses.    U.S. Pat. Appl. Publ.  (2006),     89pp.
3. Balabanov, Roumen; Strand, Krystal; Kemper, April; Lee, Ji Yeon; Popko, Brian.   Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-gamma    Journal of Neuroscience  (2006),  26(19),  5143-5152.

Note: MRF acknowledges and appreciates supplemental support provided to the Principal Investigators from the National Institutes of Health, and other non-governmental organizations, that contributed to the advances described in the publications listed above.

- Back to top -